Modern mobile QA can move beyond scripts and CI pipelines into autonomous, cloud-executed agents. Traditional QA approaches struggle with flakiness, limited coverage, slow feedback loops, and not leveraging powerful mechanisms such as React Native's split between JS and native bundles. Teams need more reliable, automated ways to validate real user flows before code reaches production. Agent-based QA provides a scalable way to continuously verify app behavior on real devices and reduce risk in fast-moving codebases. This talk shows how to design and operate QA agents that run against real iOS and Android devices hosted remotely. We’ll cover the architecture of a reliable agent, connecting Linux-based infrastructure to mobile devices running on macOS, and integrating outputs like screenshots, recordings, and logs directly into pull requests.